Relief of allergic rhinitis eg, rhinorrhea, sneezing, oronasopharyngeal irritation or itching; allergic conjunctivitis eg, lacrimation, red eye, irritation or itching; chronic idiopathic urticaria or other skin sensitivity.
Lorsedin Adult & childn ≥6 yr 1 tab once daily. Lorsedin Oral SolutionAdult & childn ≥6 yr 10 mg (10 mL) once daily. Childn 2-5 yr 5 mg (5 mL) once daily. Renal impairment w/ GFR <30 mL/min: Adult & childn >6 yr 10 mg every other day, childn 2-5 yr 5 mg every other day. Hepatic impairment: Adult & childn ≥6 yr 10 mg every other day, childn 2-5 yr 5 mg every other day.
Discontinue treatment if arrhythmia occurs. Prolonged QT interval. Avoid ethanol or w/ composition of alcohol. Avoid concomitant use w/ QT prolonging medications eg, Ca channel blockers (eg, bepridil, verapamil), TCA, cisapride, quinidine. Concomitant use w/ macrolides eg, erythromycin, clarithromycin; imidazole antifungals eg, ketoconazole, itraconazole, fluconazole; HIV PIs or any CYP450 inhibitors eg, cimetidine, metronidazole, zafirlukast, SSRIs. May affect ability to drive & use machines. Hepatic impairment. 1st trimester of pregnancy. Not recommended in lactation. Childn 2-5 yr (in management of chronic idiopathic urticaria). Childn <2 yr. Elderly.
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